Causing seizures in normal people would probably drive sales in the 16-25 crowd. I can see the ad-campaign now... kid playing TV on the couch, and you can tell he's really into the game. All of a sudden he starts shaking uncontrollably and collapses, with the sound byte "ha ha ha haha, wipeout" playing while a giant "Wipeout" logo slides onto the screen. The kid starts to get up and then the "HD" stamp (from the title) hits him on the head and knocks him back down.
If I see this as a commercial, I want my cut