Which control setting do you guys prefer for Fight Night? I just started playing the series and I feel like i can whip out the combos way better with the face buttons, and only go to the stick for haymakers. I feel like I'm missing out on something by doing it this way though. Thoughts? Anybody find that they got used to the "Total Punch Control" after a while? (With this game or previous ones)

Well, with previous ones the TPC was pretty easy to get used to. With this one, I do what you said.
I use the buttons mainly with the stick for Haymakers. But, my fingers are on the sticks a lot because that's the way I fight .
I SOMETIMES use the sticks, but not too often. With the face buttons, you are assured of what punch you are going to throw so if you fatfinger the thing, you don't throw a jab when you wanted a hook/cross.

Setup #3 for me! This game is sweet!

I also use the face buttons with the stick for the impact punches... config 5

config 4...but still testing the others

config3 here for me..so far

I can do combos better on the stick. You don't need to bring the stick back to center to start a new punch, just roll it back and forth across UP and control what type of punch by how far you bring it back. I use the buttons as well when i'm going for a specific punch (such as a hooks to the body).

config 3 over here

no one is a real figther unless you use CONFIG 1.... STICK baby...all the way....

i hate button smashers..

I use Control 5, its works for SICK parrying skills, not having to hold R to block, and I use the buttons for combos, but sometimes mix it up...like throw a right body hook with the button, then go left with the stick for a bit more power

i'd have to concur with config 5 being the way to go

Config #1, love the sticks.

config #3 is the best for all users i think