Has anyone had success in flashing this drive to read 360 games in a PC? It's actually an old drive I had laying around from a previous system build and thought I'd ask before it gets gutted out to put a spare 360 drive inside the enclosure.

This is a DH-16D2S, not to be confused with the DG-16D2S, and it will not be used inside of a 360, just to be clear.

I assume you mean to rip games. Yes, just flash with the 0800 firmware. If you mean to play 360 games on your PC, which I hope you are not asking, then no that is not possible for the same reason that you cannot put an airplane seat in your car and expect it to fly :-)

I have a DH-16D2S, and flashed LT-liteon-0800-v3.bin onto it.
Bad news, will not do a thing, nevermind noticed by windows.
Did either of you actually try this?